Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics.

نویسندگان

  • Tamas Kálai
  • Govindasamy Mugesh
  • Gouriprasanna Roy
  • Helmut Sies
  • Zoltán Berente
  • Kálmán Hideg
چکیده

Benzo[d]isoselenazol-3-ones N-substituted with sterically hindered diamagnetic and paramagnetic five- or six-membered nitroxides or their precursors, including ring-opened diselenides, exhibit synergism in glutathione peroxidase (GPx) activity.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 3 19  شماره 

صفحات  -

تاریخ انتشار 2005